Released on: February 18, 2008, 10:04 am

Press Release Author: Belinda De Leon / Trevigen, Inc.

Industry: Biotech

Press Release Summary: Trevigen launches High-Throughput PARP/Apoptosis Assays ideal
for measuring the activity of PARP in 96-well plates.

Press Release Body: Trevigen launches High-Throughput PARP/Apoptosis Assays ideal
for measuring the activity of PARP in 96-well plates. Cell extracts can be obtained
using our newly-developed, higher-throughput procedure before, during and after
apoptosis induction. During apoptosis, PARP-1 which catalyzes the NAD dependent
addition of poly (ADP-ribose) (PAR) onto various cytoplasmic and nuclear proteins,
is cleaved from its enzymatically active form (about 116 kDa), to its inactive form
(85 kDa). The HT PARP/Apoptosis Assay is an ELISA which semi-quantitatively detects
PAR deposited onto immobilized histone proteins (via PARP activity) in a 96-well
format.

Trevigen offers two formats of the HT PARP/Apoptosis Assay: Cat#4684-096-K
(Colorimetric) and Cat# 4685-096-K (Chemiluminescent). Additional histone-coated
strip wells (Cat# 4677-096-P) are available separately. For details, contact
Trevigen, at 800-873-8443, info@trevigen.com or visit the website at
www.trevigen.com.


Web Site: http://www.trevigen.com

Contact Details: Press Contact:
Belinda De Leon
800-873-8443
info@trevigen.com
www.trevigen.com

Trevigen, Inc.
8405 Helgerman Ct.
Gaithersburg, MD 20877